Relationship between DNA ploidy, expression of ki-67 antigen and gastric cancer metastasis

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The role of DNA ploidy and Ki-67 in the grading of mucoepidermoid carcinomas.

BACKGROUND The grading of mucoepidermoid carcinomas (MEC) is based on subjective microscopic evaluation of the prevalence of cell types as well as features of atypia and aggressiveness. Our study was aimed at evaluating the role of high-resolution DNA flow cytometry and Ki-67 expression in the grading of MEC. MATERIALS AND METHODS Fifty-five cases of intraoral and major salivary gland tumours...

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Relationship between AgNOR Proteins, Ki-67 Antigen, p53 Immunophenotype and Differentiation Markers in Archival Breast Carcinomas

The present study investigated (i) the relationship between standardised morphometric AgNOR parameters (argyrophilic nucleolar organiser region-associated proteins) and MIB1 growth fraction, and (ii) their correlation with immunohistochemical p53, sex steroid receptor status and histopathological differentiation grade in serial paraffin sections from 39 breast carcinomas. Ten sections were doub...

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Clinicopathological importance of Ki-67, p27, and p53 expression in gastric cancer.

BACKGROUND/AIM To assess the prognostic value of Ki-67, p27, and p53 immunoreactivity in human gastric cancer. MATERIALS AND METHODS A total of 84 patients with gastric cancer participated in our study. We categorized tumors as intestinal and diffuse types, with reference to Lauren's classification. Ki-67, p27, and p53 immunoreactivity were correlated with patient's age, tumor type, grade, ly...

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Expression of Cyclooxygenase-2, p53 and Ki-67 in Gastric Cancer

It has been reported that p53 mutation may contribute to upregulate cyclooxygenase (COX)-2 expression that is observed in malignant tissues. These molecules are involved in carcinogenesis by affecting tumor cell proliferation. The aim of this study was to examine the relationship between COX-2 or p53 expression and clinico-pathological characteristics including tumor cell proliferation in gastr...

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OBJECTIVE To investigate the relationship between the CD4+CD25+ Treg cell proportion in the peripheral blood and the clinicopathologic features of non-small cell lung cancer (NSCLC) patients and hypoxia-inducible factor-1α (HIF-1α), Ki-67 expression. PATIENTS AND METHODS Flow cytometry was used to measure the CD4+CD25+ Treg cell level in peripheral blood and immunohistochemical staining used ...

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ژورنال

عنوان ژورنال: World Journal of Gastroenterology

سال: 1999

ISSN: 1007-9327

DOI: 10.3748/wjg.v5.i1.10